Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
This position is full-time and works approximately 40 hours per week.
Department Name/Job Location:
This position is in the Department of Pediatrics, Division of Infectious Diseases. This position is for the Medical School Campus.
Malignancies develop due to accumulated DNA damage which can be caused by environmental exposures, such as sunlight and tobacco smoke, and also by the process of aging. Children rarely have excessive exposure to environmental carcinogens, so the etiology of DNA damage in pediatric cancers is often unclear. Our lab is interested not only in the sources of DNA damage that give rise to childhood malignancies, but also DNA damage responses – cellular signaling pathways activated in response to DNA mutations and breaks – that occur in cancer cells.
Our current research efforts are divided among studies of two sources of DNA damage in pediatric cancer: (1) APOBEC3 enzymes, which function within the immune system as anti-viral agents but have the capacity to mutate host cell DNA, and (2) translocations involving the MLL gene, which occur in infants with leukemia and elicit robust DNA damage responses.
The lab is focused on basic mechanisms of cancer biology with the goal of improving outcomes for children with cancer.
This position assists with the technical aspects of studies and experiments, including documentation and preparation of materials.
PRIMARY DUTIES AND RESPONSIBILITIES:
Assists with research studies, experiments and assays in cell biology, genetics, and molecular biology. This includes collection of data, preparation of solutions and set-up and maintenance of equipment.
Performs data entry and maintains data files on research.
Prepares tissue cultures, reagents, probe tests, etc.
Complies with established safety procedures and maintains required documentation on laboratory and specimen conditions.
Ensures lab conditions and equipment are properly cleaned and maintained in accordance with established procedures.
Assists with general lab maintenance and organization, including supply ordering, buffer preparation, and electronic systems for cell and reagent organization.
Participates in lab meetings and journal clubs.
Bachelor’s degree and up to one year of experience in a laboratory setting or an equivalent combination of education and experience equaling four years.
Familiarity with basic science laboratory setting (experience with specific assays is not necessary).
Demonstrated ability to work independently and communicate with laboratory staff and investigators.
Ability to maintain complete and organized records/reports.
Working knowledge of computer software and general lab equipment.
Good verbal, written communication skills.
Applicant Special Instructions:
This position works in a laboratory environment with potential exposure to biological, chemical and radioactive hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.
The hiring range for this position is $14.07 - $18.99 per hour.
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.
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